MyBioSource.com's Anti-Gelsolin antibody (monoclonal) is a Mouse monoclonal antibody. The Anti-Gelsolin antibody (monoclonal) was generated using AGEL, Gelsolin, and Gsn as the antigen. It reacts with Human, and Rabbit. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Description: Mouse IgG monoclonal antibody for Gelsolin, gelsolin (GSN) detection. Tested with WB, IHC-P, IHC-F in Human, rabbit, bovine. No cross reactivity with otherproteins. Uniprot ID: P06396
Background: Gelsolin, a protein of leukocytes, platelets, and other cells, severs actin filaments in the presence of submicromolar calcium, thereby solating cytoplasmic actin gels. A gelsolin variant with 23 more N-terminal amino acids is a plasma component probably involved in the clearance of actin, the most abundant human protein, from the circulation. Gelsolin is located in 9q34. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain